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The Mrs. William B. Astor House was a large mansion located on 840 Fifth Avenue, in the Upper East Side of New York City, New York, USA. It was originally constructed for the wife of real estate heir William Backhouse Astor, Jr., Caroline Astor. Back then, wives and widows often used their husband's name with a "Mrs." added on. Society did not expect a woman to use her first name or to support her own living expenses.